Long-term caloric restriction activates the myocardial SIRT1/AMPK/PGC-1α pathway in C57BL/6J male mice
Background: Caloric restriction (CR) can help in improving heart function. There is as yet no consensus on the mechanism of the effect of CR. Silent mating-type information regulation 1 (SIRT1), adenosine monophosphate-activated protein kinase (AMPK), and mTOR are key players in metabolic stress man...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Swedish Nutrition Foundation
2020-01-01
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Series: | Food & Nutrition Research |
Subjects: | |
Online Access: | https://foodandnutritionresearch.net/index.php/fnr/article/view/3668/10106 |