Long-term caloric restriction activates the myocardial SIRT1/AMPK/PGC-1α pathway in C57BL/6J male mice

Background: Caloric restriction (CR) can help in improving heart function. There is as yet no consensus on the mechanism of the effect of CR. Silent mating-type information regulation 1 (SIRT1), adenosine monophosphate-activated protein kinase (AMPK), and mTOR are key players in metabolic stress man...

Full description

Bibliographic Details
Main Authors: Lina Ma, Rong Wang, Hongjuan Wang, Yaxin Zhang, Zhiwei Zhao
Format: Article
Language:English
Published: Swedish Nutrition Foundation 2020-01-01
Series:Food & Nutrition Research
Subjects:
Online Access:https://foodandnutritionresearch.net/index.php/fnr/article/view/3668/10106