Physalin A regulates the Nrf2 pathway through ERK and p38 for induction of detoxifying enzymes

Physalin A regulates the Nrf2 pathway through ERK and p38 for induction of detoxifying enzymes

Abstract Background Physalin A isolated from Physalis alkekengi var. franchetii has been known to have many pharmacological properties. However, its effect through the Nrf2 pathway has not yet been elucidated. In the present study, we determined the effects of physalin A on cancer chemoprevention vi...

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Bibliographic Details
Main Authors: Ji Min Shin, Kyung-Mi Lee, Hee Ju Lee, Ji Ho Yun, Chu Won Nho
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Physalin A
Cancer chemoprevention
Quinone reductase
NF-E2-related factor 2
Extracellular signal-regulated kinase
p38 mitogen-activated protein kinase
Online Access:http://link.springer.com/article/10.1186/s12906-019-2511-y

Internet

http://link.springer.com/article/10.1186/s12906-019-2511-y

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