Tax1BP1 limits hepatic inflammation and reduces experimental hepatocarcinogenesis

Tax1BP1 limits hepatic inflammation and reduces experimental hepatocarcinogenesis

Abstract The nuclear factor kappa beta (NFκB) signaling pathway plays an important role in liver homeostasis and cancer development. Tax1-binding protein 1 (Tax1BP1) is a regulator of the NFκB signaling pathway, but its role in the liver and hepatocellular carcinoma (HCC) is presently unknown. Here...

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Main Authors: Oliver Waidmann, Thomas Pleli, Andreas Weigert, Esther Imelmann, Bianca Kakoschky, Christian Schmithals, Claudia Döring, Matthias Frank, Thomas Longerich, Verena Köberle, Martin-Leo Hansmann, Bernhard Brüne, Stefan Zeuzem, Albrecht Piiper, Ivan Dikic
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-73387-4

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https://doi.org/10.1038/s41598-020-73387-4

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