Efficient identification of neoantigen-specific T-cell responses in advanced human ovarian cancer

Efficient identification of neoantigen-specific T-cell responses in advanced human ovarian cancer

Abstract Background Efficient identification of neoantigen-specific T-cell responses in epithelial ovarian cancer (EOC) remains a challenge. Existing investigations of spontaneous T-cell response to tumor neoepitope in EOC have taken the approach of comprehensive screening all neoantigen candidates,...

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Bibliographic Details
Main Authors: Song Liu, Junko Matsuzaki, Lei Wei, Takemasa Tsuji, Sebastiano Battaglia, Qiang Hu, Eduardo Cortes, Laiping Wong, Li Yan, Mark Long, Anthony Miliotto, Nicholas W. Bateman, Shashikant B. Lele, Thinle Chodon, Richard C. Koya, Song Yao, Qianqian Zhu, Thomas P. Conrads, Jianmin Wang, George L. Maxwell, Amit A. Lugade, Kunle Odunsi
Format: Article
Language:English
Published: BMJ Publishing Group 2019-06-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Neoantigen
Ovarian cancer
CD4+ T-cells
CD8+ T-cells
Anti-tumor effect
T-cell receptor
Online Access:http://link.springer.com/article/10.1186/s40425-019-0629-6

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http://link.springer.com/article/10.1186/s40425-019-0629-6

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