Weakening impact of excessive human serum albumin (eHSA) on cisplatin and etoposide anticancer effect in C57BL/6 mice with tumor and in human NSCLC A549 cells

Excessive human serum albumin (eHSA) impact on anticancer effects is inconsistent. We explored the outcome of cisplatin (DDP)/etoposide (VP-16) plus eHSA in vivo and in vitro. C57BL/6 mice with tumor were used to compare the efficacy of DDP/VP-16 alone and DDP/VP-16+eHSA. Blood albumin was measured...

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Bibliographic Details
Main Authors: Zhen Yang, Ting Zhou, Yuanchi Cheng, Mingming Li, Xianglin Tan, Feng Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00434/full