Bridged filaments of histone-like nucleoid structuring protein pause RNA polymerase and aid termination in bacteria

Bridged filaments of histone-like nucleoid structuring protein pause RNA polymerase and aid termination in bacteria

Bacterial H-NS forms nucleoprotein filaments that spread on DNA and bridge distant DNA sites. H-NS filaments co-localize with sites of Rho-dependent termination in Escherichia coli, but their direct effects on transcriptional pausing and termination are untested. In this study, we report that bridge...

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Bibliographic Details
Main Authors: Matthew V Kotlajich, Daniel R Hron, Beth A Boudreau, Zhiqiang Sun, Yuri L Lyubchenko, Robert Landick
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-01-01
Series:eLife
Subjects:
RNAP
H-NS
rho
NusG
GreB
transcription termination
Online Access:https://elifesciences.org/articles/04970

Internet

https://elifesciences.org/articles/04970

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