BSA Nanoparticles for siRNA Delivery: Coating Effects on Nanoparticle Properties, Plasma Protein Adsorption, and In Vitro siRNA Delivery

Developing vehicles for the delivery of therapeutic molecules, like siRNA, is an area of active research. Nanoparticles composed of bovine serum albumin, stabilized via the adsorption of poly-L-lysine (PLL), have been shown to be potentially inert drug-delivery vehicles. With the primary goal of red...

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Bibliographic Details
Main Authors: Haran Yogasundaram, Markian Stephan Bahniuk, Harsh-Deep Singh, Hamidreza Montezari Aliabadi, Hasan Uludaǧ, Larry David Unsworth
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Biomaterials
Online Access:http://dx.doi.org/10.1155/2012/584060