Redosing of Fluorescein Sodium Improves Image Interpretation During Intraoperative Ex Vivo Confocal Laser Endomicroscopy of Brain Tumors

Redosing of Fluorescein Sodium Improves Image Interpretation During Intraoperative Ex Vivo Confocal Laser Endomicroscopy of Brain Tumors

BackgroundFluorescein sodium (FNa) is a fluorescence agent used with a wide-field operating microscope for intraoperative guidance and with confocal laser endomicroscopy (CLE) to evaluate brain tissue. Susceptibility of FNa to degradation over time may affect CLE image quality during prolonged surge...

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Bibliographic Details
Main Authors: Irakliy Abramov, Alexander B. Dru, Evgenii Belykh, Marian T. Park, Liudmila Bardonova, Mark C. Preul
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
brain tumors
confocal laser endomicroscopy
fluorescein sodium
fluorescence-guided neurosurgery
glioblastoma
image interpretation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.668661/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.668661/full

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