Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.

Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.

Peptidyl-prolyl isomerases catalyze the conversion between cis and trans isomers of proline. The cyclophilin family of peptidyl-prolyl isomerases is well known for being the target of the immunosuppressive drug cyclosporin, used to combat organ transplant rejection. There is great interest in both t...

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Bibliographic Details
Main Authors: Tara L Davis, John R Walker, Valérie Campagna-Slater, Patrick J Finerty, Ragika Paramanathan, Galina Bernstein, Farrell MacKenzie, Wolfram Tempel, Hui Ouyang, Wen Hwa Lee, Elan Z Eisenmesser, Sirano Dhe-Paganon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20676357/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20676357/pdf/?tool=EBI

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