Lactation during cholestasis: Role of ABC proteins in bile acid traffic across the mammary gland

Abstract Transporters involved in bile acid (BA) handling by the mammary gland are poorly understood. Here we have investigated the role of ABC proteins in blood-milk BA traffic and its sensitivity to maternal cholestasis. BA concentrations in rat and mouse serum were higher than in milk. BA profile...

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Bibliographic Details
Main Authors: Alba M. G. Blazquez, Rocio I. R. Macias, Candela Cives-Losada, Alberto de la Iglesia, Jose J. G. Marin, Maria J. Monte
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06315-8