Nonmuscle Myosin Heavy Chain IIA Recognizes Sialic Acids on Sialylated RNA Viruses To Suppress Proinflammatory Responses via the DAP12-Syk Pathway

Nonmuscle Myosin Heavy Chain IIA Recognizes Sialic Acids on Sialylated RNA Viruses To Suppress Proinflammatory Responses via the DAP12-Syk Pathway

NMHC-IIA, a subunit of nonmuscle myosin IIA (NM-IIA), takes part in diverse physiological processes, including cell movement, cell shape maintenance, and signal transduction. Recently, NMHC-IIA has been demonstrated to be a receptor or factor contributing to viral infections. Here, we identified tha...

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Bibliographic Details
Main Authors: Yingqi Liu, Rui Li, Xin-xin Chen, Yubao Zhi, Ruiguang Deng, En-min Zhou, Songlin Qiao, Gaiping Zhang
Format: Article
Language:English
Published: American Society for Microbiology 2019-05-01
Series:mBio
Subjects:
DAP12
NMHC-IIA
negative modulation
proinflammatory responses
sialic acids
sialylated RNA virus
Online Access:https://doi.org/10.1128/mBio.00574-19

Internet

https://doi.org/10.1128/mBio.00574-19

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