Activation of the Alternate Renin-Angiotensin System Correlates with the Clinical Status in Human Cirrhosis and Corrects Post Liver Transplantation

Activation of the Alternate Renin-Angiotensin System Correlates with the Clinical Status in Human Cirrhosis and Corrects Post Liver Transplantation

Introduction: Recent animal studies have shown that the alternate renin-angiotensin system (RAS) consisting of angiotensin-converting enzyme 2 (ACE2), angiotensin-(1–7) (Ang-(1–7)) and the Mas receptor is upregulated in cirrhosis and contributes to splanchnic vasodilatation and p...

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Bibliographic Details
Main Authors: Stephen Casey, Robert Schierwagen, Kai Yan Mak, Sabine Klein, Frank Uschner, Christian Jansen, Michael Praktiknjo, Carsten Meyer, Daniel Thomas, Chandana Herath, Robert Jones, Jonel Trebicka, Peter Angus
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Journal of Clinical Medicine
Subjects:
cirrhosis
portal hypertension
renin-angiotensin system
Online Access:https://www.mdpi.com/2077-0383/8/4/419

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https://www.mdpi.com/2077-0383/8/4/419

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