Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPDResearch in context

Background: The causes of poor respiratory function and COPD are incompletely understood, but it is clear that genes and the environment play a role. As DNA methylation is under both genetic and environmental control, we hypothesised that investigation of differential methylation associated with the...

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Bibliographic Details
Main Authors: Mairead L. Bermingham, Rosie M. Walker, Riccardo E. Marioni, Stewart W. Morris, Konrad Rawlik, Yanni Zeng, Archie Campbell, Paul Redmond, Heather C. Whalley, Mark J. Adams, Caroline Hayward, Ian J. Deary, David J. Porteous, Andrew M. McIntosh, Kathryn L. Evans
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419302178