Biomimetically engineered Amphotericin B nano-aggregates circumvent toxicity constraints and treat systemic fungal infection in experimental animals

Abstract Biomimetic synthesis of nanoparticles offers a convenient and bio friendly approach to fabricate complex structures with sub-nanometer precision from simple precursor components. In the present study, we have synthesized nanoparticles of Amphotericin B (AmB), a potent antifungal agent, usin...

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Bibliographic Details
Main Authors: Qamar Zia, Owais Mohammad, Mohd Ahmar Rauf, Wasi Khan, Swaleha Zubair
Format: Article
Language:English
Published: Nature Publishing Group 2017-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-11847-0