Macrophage-specific overexpression of group IIa sPLA2 increases atherosclerosis and enhances collagen deposition

Macrophage-specific overexpression of group IIa sPLA2 increases atherosclerosis and enhances collagen deposition

Atherosclerosis is a chronic inflammatory disease of the vessel wall characterized by the accumulation of lipid-laden macrophages and fibrotic material. The initiation of the disease is accompanied by the accumulation of modified lipoproteins in the vessel wall. Group IIa secretory phospholipase A2...

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Bibliographic Details
Main Authors: Stijn A.I. Ghesquiere, Marion J.J. Gijbels, Marit Anthonsen, Patrick J.J. van Gorp, Ingeborg van der Made, Berit Johansen, Marten H. Hofker, Menno P.J. de Winther
Format: Article
Language:English
Published: Elsevier 2005-02-01
Series:Journal of Lipid Research
Subjects:
atherogenesis
lipid modification
inflammation
secretory phospholipase A2
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520340529

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http://www.sciencedirect.com/science/article/pii/S0022227520340529

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