Prevalence and coexistence of KRAS, BRAF, PIK3CA, NRAS, TP53, and APC mutations in Indian colorectal cancer patients: Next-generation sequencing–based cohort study

Colorectal cancer incidences are on a rise in India. In this study, we have analyzed the mutation frequencies of six potential biomarkers, their coexistence, association with clinicopathological characteristics, and tumor location in Indian colorectal cancer patients. Next-generation sequencing was...

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Bibliographic Details
Main Authors: Mayank Jauhri, Akanksha Bhatnagar, Satish Gupta, Manasa BP, Sachin Minhas, Yogender Shokeen, Shyam Aggarwal
Format: Article
Language:English
Published: IOS Press 2017-02-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317692265