Leishmania donovani Activates Hypoxia Inducible Factor-1α and miR-210 for Survival in Macrophages by Downregulation of NF-κB Mediated Pro-inflammatory Immune Response

Leishmania donovani Activates Hypoxia Inducible Factor-1α and miR-210 for Survival in Macrophages by Downregulation of NF-κB Mediated Pro-inflammatory Immune Response

Micro RNAs (miRNAs) have emerged as a critical regulator of several biological processes in both animals and plants. They have also been associated with regulation of immune responses in many human diseases during recent years. Visceral leishmaniasis (VL) is the most severe form of leishmaniasis, wh...

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Bibliographic Details
Main Authors: Vinod Kumar, Ajay Kumar, Sushmita Das, Ashish Kumar, Kumar Abhishek, Sudha Verma, Abhishek Mandal, Rakesh K. Singh, Pradeep Das
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Microbiology
Subjects:
HIF-1α
miR-210
NF-κB
cytokines
visceral leishmaniasis
macrophages
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00385/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2018.00385/full

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