Interferon-lambda3 (IFN-λ3) and its cognate receptor subunits in tree shrews (Tupaia belangeri): genomic sequence retrieval, molecular identification and expression analysis.

Type III IFNs (IFN-λs) constitute a new subfamily with antiviral activities by signaling through a unique receptor complex composed of IFN-λs receptor 1 (IFNλR1) and interleukin-10 receptor 2 (IL10R2). As tree shrews (Tupaia belangeri) have shown susceptiblility to several human viruses, they are a...

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Bibliographic Details
Main Authors: Ming-Li Li, Wen-Wen Xu, Yue-Dong Gao, Yan Guo, Wen-Ju Wang, Chao Wang, Shi-You Jiang, Andrew Willden, Jing-Fei Huang, Hua-Tang Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23555878/pdf/?tool=EBI