Circ_0116061 regulated the proliferation, apoptosis, and inflammation of osteoarthritis chondrocytes through regulating the miR-200b-3p/SMURF2 axis

Circ_0116061 regulated the proliferation, apoptosis, and inflammation of osteoarthritis chondrocytes through regulating the miR-200b-3p/SMURF2 axis

Abstract Background Circular RNA (circRNA) has been shown to be associated with osteoarthritis (OA) progression. Circ_0116061 has been found to be highly expressed in OA cartilage tissues, but its role and mechanism in OA progression remain unclear. Methods Expression levels of circ_0116061, microRN...

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Bibliographic Details
Main Authors: Wei Zheng, Guanhua Hou, Yong Li
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Osteoarthritis
Chondrocytes
Circ_0116061
MiR-200b-3p
SMURF2
Online Access:https://doi.org/10.1186/s13018-021-02391-9

Internet

https://doi.org/10.1186/s13018-021-02391-9

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