Campylobacter concisus upregulates PD-L1 mRNA expression in IFN-γ sensitized intestinal epithelial cells and induces cell death in esophageal epithelial cells

Introduction: Campylobacter concisus is an oral bacterium that is associated with inflammatory bowel disease (IBD) and Barrett’s esophagus (BE). Programmed cell death ligand-1 (PD-L1) is an immune checkpoint protein that is used by tumor cells for immune evasion and has increased expression in patie...

Full description

Bibliographic Details
Main Authors: Seul A Lee, Fang Liu, Doo Young Yun, Stephen M Riordan, Alfred Chin Yen Tay, Lu Liu, Cheok Soon Lee, Li Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Journal of Oral Microbiology
Subjects:
Online Access:http://dx.doi.org/10.1080/20002297.2021.1978732