P2RX7: expression responds to sleep deprivation and associates with rapid cycling in bipolar disorder type 1.

P2RX7: expression responds to sleep deprivation and associates with rapid cycling in bipolar disorder type 1.

Rapid cycling is a severe form of bipolar disorder with an increased rate of episodes that is particularly treatment-responsive to chronotherapy and stable sleep-wake cycles. We hypothesized that the P2RX7 gene would be affected by sleep deprivation and be implicated in rapid cycling.To assess wheth...

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Bibliographic Details
Main Authors: Lena Backlund, Catharina Lavebratt, Louise Frisén, Pernilla Nikamo, Dzana Hukic Sudic, Lil Träskman-Bendz, Mikael Landén, Gunnar Edman, Marquis P Vawter, Urban Ösby, Martin Schalling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3429455?pdf=render

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http://europepmc.org/articles/PMC3429455?pdf=render

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