Hyperhomocysteinemia, Deep Vein Thrombosis and Vitamin B12 Deficiency in a Metformin-treated Diabetic Patient
Vitamin B12 deficiency may be induced by long-term use of metformin, which may in turn lead to hyper-homocysteinemia. Thus, hyperhomocysteinemia may increase the risk of vascular thrombosis in diabetic patients, when metformin is used and a homozygous methylenetetrahydrofolate reductase (MTHFR) C677...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2007-09-01
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| Series: | Journal of the Formosan Medical Association |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S092966460860039X |