Diverse type 2 diabetes genetic risk factors functionally converge in a phenotype-focused gene network.

Type 2 Diabetes (T2D) constitutes a global health burden. Efforts to uncover predisposing genetic variation have been considerable, yet detailed knowledge of the underlying pathogenesis remains poor. Here, we constructed a T2D phenotypic-linkage network (T2D-PLN), by integrating diverse gene functio...

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Bibliographic Details
Main Authors: Cynthia Sandor, Nicola L Beer, Caleb Webber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5667928?pdf=render