Broad auto-reactive IgM responses are common in critically ill patients, including those with COVID-19

Summary: The pathogenesis of severe coronavirus disease 2019 (COVID-19) remains poorly understood. While several studies suggest that immune dysregulation plays a central role, the key mediators of this process are yet to be defined. Here, we demonstrate that plasma from a high proportion (93%) of c...

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Bibliographic Details
Main Authors: Andrew Kam Ho Wong, Isaac Woodhouse, Frank Schneider, Deanna A. Kulpa, Guido Silvestri, Cheryl L. Maier
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Cell Reports Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2666379121001646