Mutant Prevention Concentrations of Doripenem and Meropenem Alone and in Combination with Colistin (Polymyxin E), Levofloxacin and Tobramycin in Pseudomonas aeruginosa

BACKGROUND: With a limited number of available antimicrobial agents to treat Pseudomonas aeruginosa infections, the prevention of emergence of antimicrobial resistance and its subsequent spread is critical. In the present study, the mutant prevention concentration (MPC) of doripenem was examined and...

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Bibliographic Details
Main Authors: George G Zhanel, Vibhu Vishisht, Ed Tam, Daryl J Hoban, James A Karlowsky
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2009/801612