Neuromodulation of excitatory synaptogenesis in striatal development

Neuromodulation of excitatory synaptogenesis in striatal development

Dopamine is released in the striatum during development and impacts the activity of Protein Kinase A (PKA) in striatal spiny projection neurons (SPNs). We examined whether dopaminergic neuromodulation regulates activity-dependent glutamatergic synapse formation in the developing striatum. Systemic i...

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Bibliographic Details
Main Authors: Yevgenia Kozorovitskiy, Rui Peixoto, Wengang Wang, Arpiar Saunders, Bernardo L Sabatini
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-11-01
Series:eLife
Subjects:
basal ganglia
circuit development
corticostriatal
dopamine
pka
Online Access:https://elifesciences.org/articles/10111

Internet

https://elifesciences.org/articles/10111

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