A system for creating stable cell lines that express a gene of interest from a bidirectional and regulatable herpes simplex virus type 1 promoter.

A system for creating stable cell lines that express a gene of interest from a bidirectional and regulatable herpes simplex virus type 1 promoter.

Expression systems used to study the biological function of a gene of interest can have limited utility due to three major factors: i) weak or heterogeneous gene expression; ii) poorly controlled gene expression; and iii) low efficiencies of stable integration and persistent expression. We envisione...

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Bibliographic Details
Main Authors: Christopher B Chambers, William P Halford, Joshua Geltz, Olga Villamizar, Jeffrey Gross, Alison Embalabala, Edward Gershburg, Andrew Wilber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4378986?pdf=render

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http://europepmc.org/articles/PMC4378986?pdf=render

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