Mild hypothermia attenuates mitochondrial oxidative stress by protecting respiratory enzymes and upregulating MnSOD in a pig model of cardiac arrest.

Mild hypothermia is the only effective treatment confirmed clinically to improve neurological outcomes for comatose patients with cardiac arrest. However, the underlying mechanism is not fully elucidated. In this study, our aim was to determine the effect of mild hypothermia on mitochondrial oxidati...

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Bibliographic Details
Main Authors: Ping Gong, Chun-Sheng Li, Rong Hua, Hong Zhao, Zi-Ren Tang, Xue Mei, Ming-Yue Zhang, Juan Cui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3332059?pdf=render