Mild hypothermia attenuates mitochondrial oxidative stress by protecting respiratory enzymes and upregulating MnSOD in a pig model of cardiac arrest.
Mild hypothermia is the only effective treatment confirmed clinically to improve neurological outcomes for comatose patients with cardiac arrest. However, the underlying mechanism is not fully elucidated. In this study, our aim was to determine the effect of mild hypothermia on mitochondrial oxidati...
Main Authors: | Ping Gong, Chun-Sheng Li, Rong Hua, Hong Zhao, Zi-Ren Tang, Xue Mei, Ming-Yue Zhang, Juan Cui |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3332059?pdf=render |
Similar Items
-
MnSOD upregulation induces autophagic programmed cell death in senescent keratinocytes.
by: Emeric Deruy, et al.
Published: (2010-01-01) -
Tetramerization reinforces the dimer interface of MnSOD.
by: Yuewei Sheng, et al.
Published: (2013-01-01) -
The Role of MnSOD in T Cell Development and T Cell Activation
by: Ya-Ching Huang, et al.
Published: (2001) -
MnSOD AND AUTOPHAGY IN PREVENTION OF OXIDATIVE MITOCHONDRIAL INJURIES INDUCED BY UVB IN MURINE SKIN
by: Bakthavatchalu, Vasudevan
Published: (2012) -
The Functional Role of MnSOD as a Biomarker of Human Diseases and Therapeutic Potential of a New Isoform of a Human Recombinant MnSOD
by: Antonella Borrelli, et al.
Published: (2014-01-01)