An inducible Cre mouse line to sparsely target nervous system cells, including Remak Schwann cells

Abstract Nerves of the peripheral nervous system contain two classes of Schwann cells: myelinating Schwann cells that ensheath large caliber axons and generate the myelin sheath, and Remak Schwann cells that surround smaller axons and do not myelinate. While tools exist for genetic targeting of Schw...

Full description

Bibliographic Details
Main Authors: Darshan Sapkota, Joseph D. Dougherty
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Neural Development
Subjects:
Cre
Online Access:http://link.springer.com/article/10.1186/s13064-020-00140-y