Reactive-oxygen-species-mediated P. aeruginosa killing is functional in human cystic fibrosis macrophages.

Pseudomonas aeruginosa is the most common pathogen for chronic lung infection in cystic fibrosis (CF) patients. About 80% of adult CF patients have chronic P. aeruginosa infection, which accounts for much of the morbidity and most of the mortality. Both bacterial genetic adaptations and defective in...

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Main Authors: Noemi Cifani, Barbara Pompili, Marco Anile, Miriam Patella, Daniele Diso, Federico Venuta, Giuseppe Cimino, Serena Quattrucci, Enea Gino Di Domenico, Fiorentina Ascenzioni, Paola Del Porto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23977124/pdf/?tool=EBI