Modulation of Capsaicin-Evoked Visceral Pain and Referred Hyperalgesia by Protease-Activated Receptors 1 and 2

Modulation of Capsaicin-Evoked Visceral Pain and Referred Hyperalgesia by Protease-Activated Receptors 1 and 2

Protease-activated receptors (PARs) 1 and 2 are expressed in capsaicin-sensitive sensory neurons, being anti- and pro-nociceptive, respectively. Given the possible cross talk between PAR-2 and capsaicin receptors, we investigated if PAR-2 activation could facilitate capsaicin-evoked visceral pain an...

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Bibliographic Details
Main Authors: Naoyuki Kawao, Hisao Ikeda, Tomoko Kitano, Ryotaro Kuroda, Fumiko Sekiguchi, Kazuo Kataoka, Yoshihisa Kamanaka, Atsufumi Kawabata
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319324958

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http://www.sciencedirect.com/science/article/pii/S1347861319324958

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