Deletions in Genes Participating in Innate Immune Response Modify the Clinical Course of Andes Orthohantavirus Infection

Andes orthohantavirus (ANDV) is an important human pathogen causing hantavirus cardiopulmonary syndrome (HCPS) with a fatality rate of 30% in Chile. Around 60% of all cases have a severe clinical course, while the others have a mild clinical course. The main goal of this study was to understand if t...

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Bibliographic Details
Main Authors: Grazielle Esteves Ribeiro, Luis Edgardo Leon, Ruth Perez, Analia Cuiza, Pablo Agustin Vial, Marcela Ferres, Gregory J. Mertz, Cecilia Vial
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/11/8/680