Identification of novel B-cell epitope in gp85 of subgroup J avian leukosis virus and its application in diagnosis of disease

Identification of novel B-cell epitope in gp85 of subgroup J avian leukosis virus and its application in diagnosis of disease

Abstract Background The gp85 is the main envelope protein of avian leukosis subgroup J (ALV-J) involved in virus neutralization. Here, we mapped the epitope in ALV-J gp85 by ELISA using synthetic peptides and developed epitope based diagnostic methods for ALV-J infection. Results The results reveale...

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Bibliographic Details
Main Authors: Kun Qian, Xue Tian, Hongxia Shao, Jianqiang Ye, Yongxiu Yao, Venugopal Nair, Aijian Qin
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Veterinary Research
Subjects:
Avian leukosis virus subgroup J
B-cell epitope mapping
Epitope-based peptide ELISA
Antibody detection
Online Access:http://link.springer.com/article/10.1186/s12917-018-1622-x

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http://link.springer.com/article/10.1186/s12917-018-1622-x

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