Importance of Autophagy in Mediating Human Immunodeficiency Virus (HIV) and Morphine-Induced Metabolic Dysfunction and Inflammation in Human Astrocytes

Importance of Autophagy in Mediating Human Immunodeficiency Virus (HIV) and Morphine-Induced Metabolic Dysfunction and Inflammation in Human Astrocytes

Under physiological conditions, the function of astrocytes in providing brain metabolic support is compromised under pathophysiological conditions caused by human immunodeficiency virus (HIV) and opioids. Herein, we examined the role of autophagy, a lysosomal degradation pathway important for cellul...

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Bibliographic Details
Main Authors: Myosotys Rodriguez, Jessica Lapierre, Chet Raj Ojha, Hary Estrada-Bueno, Seth M. Dever, David A. Gewirtz, Fatah Kashanchi, Nazira El-Hage
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Viruses
Subjects:
autophagy
human immunodeficiency virus
neurotransmitters
inflammation
morphine
astrocytes
Online Access:https://www.mdpi.com/1999-4915/9/8/201

Internet

https://www.mdpi.com/1999-4915/9/8/201

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