Mutation of the N-Terminal Region of Chikungunya Virus Capsid Protein: Implications for Vaccine Design

Mosquito-transmitted chikungunya virus (CHIKV) is an arthritogenic alphavirus of the Togaviridae family responsible for frequent outbreaks of arthritic disease in humans. Capsid protein, a structural protein encoded by the CHIKV RNA genome, is able to translocate to the host cell nucleolus. In encep...

Full description

Bibliographic Details
Main Authors: Adam Taylor, Xiang Liu, Ali Zaid, Lucas Y. H. Goh, Jody Hobson-Peters, Roy A. Hall, Andres Merits, Suresh Mahalingam, Diane E. Griffin
Format: Article
Language:English
Published: American Society for Microbiology 2017-02-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/1/e01970-16