Maternal folate genes and aberrant DNA hypermethylation in pediatric acute lymphoblastic leukemia.

Maternal folate genes and aberrant DNA hypermethylation in pediatric acute lymphoblastic leukemia.

BACKGROUND:There is evidence that maternal genotypes in folate-related genes are associated with pediatric acute lymphoblastic leukemia (ALL) independent of offspring genotype. We evaluated the relationship between maternal genotypes in methionine synthase (MTR) and DNA methylation status in ALL to...

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Bibliographic Details
Main Authors: Jeremy M Schraw, Teresa T Yiu, Philip J Lupo, Spiridon Tsavachidis, Rachel Rau, Melissa L Bondy, Karen R Rabin, Lanlan Shen, Michael E Scheurer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5953491?pdf=render

Internet

http://europepmc.org/articles/PMC5953491?pdf=render

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