Method for Therapeutic Drug Monitoring of Voriconazole and its Primary Metabolite Voriconazole-N-oxide in Human Serum using LC-MS/MS
OBJECTIVES: his study aims to present a strategy to optimize a liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) method for voriconazole and voriconazole-N-oxide with an stable isotopically labelled internal standard. METHODS: Protein precipitation was used as extraction method...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Betasciencepress Publishers
2018-10-01
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| Series: | Journal of Applied Bioanalysis |
| Subjects: | |
| Online Access: | https://doi.org/10.17145/jab.18.016 |