Type I interferon-dependent gene MxA in perinatal HIV-infected patients under antiretroviral therapy as marker for therapy failure and blood plasmacytoid dendritic cells depletion

Type I interferon-dependent gene MxA in perinatal HIV-infected patients under antiretroviral therapy as marker for therapy failure and blood plasmacytoid dendritic cells depletion

<p>Abstract</p> <p>Background</p> <p>To determine the role of interferon-alpha in controlling HIV infection we phenotypically and functionally analyzed circulating plasmacytoid dendritic cells (pDC), which are known to be the highest interferon-alpha producing cells, in...

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Bibliographic Details
Main Authors: Plebani Alessandro, Lonardi Silvia, Spinelli Elena, Chiarini Marco, Sottini Alessandra, Serana Federico, Facchetti Fabio, Ghidini Claudia, Badolato Raffaele, Caimi Luigi, Imberti Luisa
Format: Article
Language:English
Published: BMC 2008-09-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/6/1/49

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http://www.translational-medicine.com/content/6/1/49

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