Two cellular resource-based models linking growth and parts characteristics aids the study and optimisation of synthetic gene circuits
A major challenge in synthetic genetic circuit development is the inter-dependency between heterologous gene expressions by circuits and host's growth rate. Increasing heterologous gene expression increases burden to the host, resulting in host growth reduction; which reduces overall heterologo...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2017-03-01
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| Series: | Engineering Biology |
| Subjects: | |
| Online Access: | https://digital-library.theiet.org/content/journals/10.1049/enb.2017.0005 |