Two cellular resource-based models linking growth and parts characteristics aids the study and optimisation of synthetic gene circuits
A major challenge in synthetic genetic circuit development is the inter-dependency between heterologous gene expressions by circuits and host's growth rate. Increasing heterologous gene expression increases burden to the host, resulting in host growth reduction; which reduces overall heterologo...
Main Authors: | Huijuan Wang, Maurice H.T. Ling, Tze Kwang Chua, Chueh Loo Poh |
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Format: | Article |
Language: | English |
Published: |
Wiley
2017-03-01
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Series: | Engineering Biology |
Subjects: | |
Online Access: | https://digital-library.theiet.org/content/journals/10.1049/enb.2017.0005 |
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