Reduced binding of the endolysin LysTP712 to Lactococcus lactis ΔftsH contributes to phage resistance

Reduced binding of the endolysin LysTP712 to Lactococcus lactis ΔftsH contributes to phage resistance

Absence of the membrane protease FtsH in Lactococcus lactis hinders release of the bacteriophage TP712. In this work we have analysed the mechanism responsible for the non-lytic phenotype of L. lactis ΔftsH after phage infection. The lytic cassette of TP712 contains a putative antiholin-pinholin sys...

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Bibliographic Details
Main Authors: CLARA eROCES, Ana Belén Campelo, Susana eEscobedo, Udo eWegmann, Pilar eGarcía, Ana eRodriguez, Beatriz eMartínez
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Microbiology
Subjects:
Lactococcus
cell surface
phage resistance
endolysin
FtsH
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00138/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00138/full

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