A multiepitope peptide vaccine against HCV stimulates neutralizing humoral and persistent cellular responses in mice

A multiepitope peptide vaccine against HCV stimulates neutralizing humoral and persistent cellular responses in mice

Abstract Background Although DAAs hold promise to significantly reduce rates of chronic HCV infections, its eradication still requires development of an effective vaccine. Prolonged T cell responses and cross neutralizing antibodies are ideal for vaccination against the infection. We aimed to design...

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Bibliographic Details
Main Authors: Reham M. Dawood, Rehab I. Moustafa, Tawfeek H. Abdelhafez, Reem El-Shenawy, Yasmine El-Abd, Noha G. Bader El Din, Jean Dubuisson, Mostafa K. El Awady
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Infectious Diseases
Subjects:
HCV
Vaccine
Humoral response
Cellular response
Online Access:http://link.springer.com/article/10.1186/s12879-019-4571-5

Internet

http://link.springer.com/article/10.1186/s12879-019-4571-5

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