RNA synthesis is modulated by G-quadruplex formation in Hepatitis C virus negative RNA strand

Abstract DNA and RNA guanine-rich oligonucleotides can form non-canonical structures called G-quadruplexes or “G4” that are based on the stacking of G-quartets. The role of DNA and RNA G4 is documented in eukaryotic cells and in pathogens such as viruses. Yet, G4 have been identified only in a few R...

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Bibliographic Details
Main Authors: Chloé Jaubert, Amina Bedrat, Laura Bartolucci, Carmelo Di Primo, Michel Ventura, Jean-Louis Mergny, Samir Amrane, Marie-Line Andreola
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-26582-3