pH-Triggered Sheddable Shielding System for Polycationic Gene Carriers

pH-Triggered Sheddable Shielding System for Polycationic Gene Carriers

For improving the therapeutic efficiency of tumors and decreasing undesirable side effects, ternary complexes were developed by coating pH-sensitive PEG-b-PLL-g-succinylsulfathiazole (hereafter abbreviated as PPSD) with DNA/PEI polyplexes via electrostatic interaction. PPSD can efficiently shield th...

Full description

Bibliographic Details
Main Authors: Jialiang Xia, Huayu Tian, Jie Chen, Lin Lin, Zhaopei Guo, Bing Han, Hongyan Yang, Zongcai Feng
Format: Article
Language:English
Published: MDPI AG 2016-04-01
Series:Polymers
Subjects:
gene delivery
shielding system
pH-sensitive
Online Access:http://www.mdpi.com/2073-4360/8/4/141

Internet

http://www.mdpi.com/2073-4360/8/4/141

Similar Items