Nilvadipine suppresses inflammation via inhibition of P-SYK and restores spatial memory deficits in a mouse model of repetitive mild TBI

Nilvadipine suppresses inflammation via inhibition of P-SYK and restores spatial memory deficits in a mouse model of repetitive mild TBI

Abstract Repeated exposure to mild TBI (mTBI) has been linked to an increased risk of Alzheimer’s disease (AD), chronic traumatic encephalopathy (CTE) and other neurodegenerative diseases. Some pathological features typically observed in AD have been found in postmortem brains of TBI and CTE, hence...

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Bibliographic Details
Main Authors: Alexander Morin, Benoit Mouzon, Scott Ferguson, Daniel Paris, Mackenzie Browning, William Stewart, Mike Mullan, Fiona Crawford
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Acta Neuropathologica Communications
Online Access:http://link.springer.com/article/10.1186/s40478-020-01045-x

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http://link.springer.com/article/10.1186/s40478-020-01045-x

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