Influence of the spacer region between the Shine–Dalgarno box and the start codon for fine‐tuning of the translation efficiency in Escherichia coli

Summary Translation efficiency contributes several orders of magnitude difference in the overall yield of exogenous gene expression in bacteria. In diverse bacteria, the translation initiation site, whose sequence is the primary determinant of the translation performance, is comprised of the start c...

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Bibliographic Details
Main Authors: Ekaterina S. Komarova, Zoya S. Chervontseva, Ilya A. Osterman, Sergey A. Evfratov, Maria P. Rubtsova, Timofei S. Zatsepin, Tatiana A. Semashko, Elena S. Kostryukova, Alexey A. Bogdanov, Mikhail S. Gelfand, Olga A. Dontsova, Petr V. Sergiev
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Microbial Biotechnology
Online Access:https://doi.org/10.1111/1751-7915.13561