Pazopanib, a Receptor Tyrosine Kinase Inhibitor, Suppresses Tumor Growth through Angiogenesis in Dedifferentiated Liposarcoma Xenograft Models

Pazopanib, a Receptor Tyrosine Kinase Inhibitor, Suppresses Tumor Growth through Angiogenesis in Dedifferentiated Liposarcoma Xenograft Models

INTRODUCTION: The rarity of dedifferentiated liposarcoma (DDLPS) and the lack of experimental DDLPS models limit the development of novel therapeutic strategies. Pazopanib (PAZ) is a tyrosine kinase inhibitor that is approved for the treatment of non-adipocytic advanced soft tissue sarcoma. The act...

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Bibliographic Details
Main Authors: Haifu Li, Agnieszka Wozniak, Raf Sciot, Jasmien Cornillie, Jasmien Wellens, Thomas Van Looy, Ulla Vanleeuw, Marguerite Stas, Daphne Hompes, Maria Debiec-Rychter, Patrick Schöffski
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523314001004

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http://www.sciencedirect.com/science/article/pii/S1936523314001004

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