Molecular safeguarding of CRISPR gene drive experiments

Molecular safeguarding of CRISPR gene drive experiments

CRISPR-based homing gene drives have sparked both enthusiasm and deep concerns due to their potential for genetically altering entire species. This raises the question about our ability to prevent the unintended spread of such drives from the laboratory into a natural population. Here, we experiment...

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Bibliographic Details
Main Authors: Jackson Champer, Joan Chung, Yoo Lim Lee, Chen Liu, Emily Yang, Zhaoxin Wen, Andrew G Clark, Philipp W Messer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-01-01
Series:eLife
Subjects:
safe drives
gene drive
CRISPR
synthetic targets
split drive
Online Access:https://elifesciences.org/articles/41439

Internet

https://elifesciences.org/articles/41439

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