Implementation of a single quad MS detector in routine QC analysis of peptide drugs

Implementation of a single quad MS detector in routine QC analysis of peptide drugs

A newly developed single quad mass spectrometry (MS) detector was coupled to a ultra-high performance liquid chromatography (UPLC) system and implemented in the routine quality control (QC) and impurity analysis of four therapeutic peptides, namely bleomycin sulfate, tyrothricin, vancomycin HCl and...

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Bibliographic Details
Main Authors: Matthias D’Hondt, Bert Gevaert, Evelien Wynendaele, Bart De Spiegeleer
Format: Article
Language:English
Published: Elsevier 2016-02-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Quality control
Peptide
Impurity profiling
Single quad MS detector
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177915300071

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http://www.sciencedirect.com/science/article/pii/S2095177915300071

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